Patterns of multimorbidity in association with falls among the middle-aged and older adults: results from the China Health and Retirement Longitudinal Study | BMC Public Health


  • Tinetti ME, Speechley M, Ginter SF. Risk factors for falls in older people living in the community. N Engl. J Med. 1988;319(26):1701-7.

    Article Google Scholar

  • Gale CR, Cooper C, Aihie Sayer A. Prevalence and risk factors for falls in older men and women: The English Longitudinal Study of Aging. age aging. 2016;45(6):789-94.

    Article Google Scholar

  • Tinetti ME, Inouye SK, Gill TM, Doucette JT. Common risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. yama. 1995;273(17):1348-53.

    Article Google Scholar

  • Fang EF, Scheibye-Knudsen M, Jahn HJ, Li J, Ling L, Guo H, Zhu X, Preedy V, Lu H, Bohr VA, et al. A Research Agenda for Aging in China in the 21st Century. Aging Res Rev. 2015;24(Pt B):197-205.

    Article Google Scholar

  • Wang J, Chen Z, Song Y. Falls among the elderly in mainland China: epidemiology, risk factors, and clinical strategies. Aging Res Rev. 2010;9(Suppl 1):S13-17.

    Article Google Scholar

  • Valderas JM, Starfield B, Sibbald B, Salisbury C, Roland M. Defining comorbidity: implications for understanding health and health services. Ann Fam Med. 2009;7(4):357-63.

    Article Google Scholar

  • Ek S, Rizzuto D, Fratiglioni L, Johnell K, Xu W, Welmer AK. Risk Profiles for Harmful Falls in People Over 60: A Population-Based Cohort Study. J. Gerontol. A. Biol. Sci. Med.Sci. 2018;73(2):233-9.

    Article Google Scholar

  • Paliwal Y, Slattum PW, Ratliff SM. Chronic health conditions as a risk factor for falls among community-dwelling older adults in the US: A zero-inflated regression modeling approach. Biomed Res Int. 2017;2017:5146378.

    Article Google Scholar

  • Juul-Larsen HG, Andersen O, Bandholm T, Bodilsen AC, Kallemose T, Jørgensen LM, Klausen HH, Gilkes H, Petersen J. Differences in functioning and recovery profiles between multimorbidity patterns in elderly medical patients in the first year after acute admission-A exploratory latent class analysis. Arch Gerontol Geriatr. 2020;86:103956.

    Article Google Scholar

  • Prados-Torres A, Calderón-Larrañaga A, Hancco-Saavedra J, Poblador-Plou B, van den Akker M. Patterns of multimorbidity: a systematic review. J Clin Epidemiol. 2014;67(3):254-66.

    Also Read :  Review team seeks stakeholder input on FDA and announces public meeting

    Article Google Scholar

  • Kriegsman DM, Deeg DJ, Stalman WA. Comorbidity of somatic chronic diseases and decrease in physical functioning:; the Longitudinal Aging Study Amsterdam. J Clin Epidemiol. 2004;57(1):55-65.

    Article Google Scholar

  • Yao SS, Meng X, Cao GY, Huang ZT, Chen ZS, Han L, Wang K, Su HX, Luo Y, Hu Y, et al. Associations between multimorbidity and physical capacity in older Chinese adults. Int J Environ Res Public Health. 2020;17(12):4546.

    Article Google Scholar

  • Jackson CA, Jones M, Tooth L, Mishra GD, Byles J, Dobson A. Patterns of multimorbidity are differentially associated with functioning and decline in a longitudinal cohort of older women. age aging. 2015;44(5):810-6.

    Article Google Scholar

  • Calderón-Larrañaga A, Vetrano DL, Ferrucci L, Mercer SW, Marengoni A, Onder G, Eriksdotter M, Fratiglioni L. Multimorbidity and functional impairment – bidirectional interplay, synergistic effects and common pathways. J Intern Med. 2019;285(3):255-71.

    Article Google Scholar

  • Yao SS, Cao GY, Han L, Chen ZS, Huang ZT, Gong P, Hu Y, Xu B. Prevalence and patterns of multimorbidity in a nationally representative sample of elderly Chinese: results from the China Health and Retirement Longitudinal Study. J. Gerontol. A. Biol. Sci. Med.Sci. 2020;75(10):1974-80.

    Article Google Scholar

  • Chen X, Crimmins E, Hu PP, Kim JK, Meng Q, Strauss J, Wang Y, Zeng J, Zhang Y, Zhao Y. Venous blood-based biomarkers in the longitudinal study of health and retirement in China: rationale, design, and results from the 2015 wave. Am J Epidemiol. 2019;188(11):1871-7.

    Article Google Scholar

  • Zhao Y, Hu Y, Smith JP, Strauss J, Yang G. Cohort profile: the China Health and Retirement Longitudinal Study (CHARLS). Int J Epidemiol. 2014;43(1):61-8.

    Article Google Scholar

  • Chen H, Mui AC. Factorial Validity of the Center for Epidemiological Studies Short Form Depression Scale in the Elderly Population in China. Int psychogeriatr. 2014;26(1):49-57.

    Article Google Scholar

    Also Read :  Increased pre-chemotherapy inflammatory biomarkers (IL-6 and CRP) correlated to increased risk of frailty post-chemotherapy in older breast cancer patients

  • Immonen M, Haapea M, Similä H, Enwald H, Keränen N, Kangas M, Jämsä T, Korpelainen R. Association between chronic diseases and falls in a sample of elderly in Finland. BMC Geriatr. 2020;20(1):225.

    Article Google Scholar

  • Lawlor DA, Patel R, Ebrahim S. Association between falls in older women and chronic illness and drug use: cross-sectional study. BMJ (Clin. Res. ed.). 2003;327(7417):712-7.

    Article Google Scholar

  • Abad-Díez JM, Calderón-Larrañaga A, Poncel-Falcó A, Poblador-Plou B, Calderón-Meza JM, Sicras-Mainar A, Clerencia-Sierra M, Prados-Torres A. Age and sex differences in prevalence and patterns of multimorbidity in the elderly population. BMC Geriatr. 2014;14:75.

    Article Google Scholar

  • Park B, Lee HA, Park H. Use of latent class analysis to identify multimorbidity patterns and associated factors in Korean adults aged 50 and older. Plus one. 2019;14(11):e0216259.

    Article Google Scholar

  • Fried TR, O’Leary J, Towle V, Goldstein MK, Trentalange M, Martin DK. Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review. J Am Geriatric Soc. 2014;62(12):2261-72.

    Article Google Scholar

  • Montero-Odasso M, Sarquis-Adamson Y, Song HY, Bray NW, Pieruccini-Faria F, Speechley M. Polypharmacy, Gait performance and falls in community-dwelling older adults. Gait and brain study results. J Am Geriatric Soc. 2019;67(6):1182-8.

    Article Google Scholar

  • Zia A, Kamaruzzaman SB, Tan MP. Polypharmacy and falls in the elderly: balance between evidence-based medicine and risk of falls. Postgraduate Med. 2015;127(3):330–7.

    Article Google Scholar

  • Rajoo SS, Wee ZJ, Lee PSS, Wong FY, Lee ES. A systematic review of patterns of associative multimorbidity in Asia. Biomed Res Int. 2021;2021:6621785.

    Article Google Scholar

  • Chen H, Cheng M, Zhuang Y, Broad JB. Multimorbidity among middle-aged and elderly people in urban China: prevalence, characteristics, and health service utilization. Geriatrician Gerontol Int. 2018;18(10):1447-52.

    Article Google Scholar

  • Jansen S, Bhangu J, de Rooij S, Daams J, Kenny RA, van der Velde N. The Association of Cardiovascular Disorders and Falls: A Systematic Review. J Am Med Dir Assoc. 2016;17(3):193-9.

    Also Read :  EHNAC Releases New 2023 Accreditation Criteria Versions for Public Review Through November 28

    Article Google Scholar

  • Honey H, Antonini A, Martinez-Martin P, Forgacs I, Faye GC, Fox T, Fox K, Mancini F, Canesi M, Odin P, et al. Intrajejunal levodopa infusion in Parkinson’s disease: a multicenter pilot study of effects on non-motor symptoms and quality of life. MovDis. 2009;24(10):1468-74.

    Article Google Scholar

  • Yang Y, Hu X, Zhang Q, Zou R. Diabetes mellitus and risk of falls in older adults: a systematic review and meta-analysis. age aging. 2016;45(6):761-7.

    Article Google Scholar

  • Brignole M, Moya A, de Lange FJ, Deharo JC, Elliott PM, Fanciulli A, Fedorowski A, Furlan R, Kenny RA, Martín A, et al. 2018 ESC Guidelines for the Diagnosis and Management of Syncope. Eur Heart J 2018;39(21):1883-948.

    Article Google Scholar

  • Roig M, Eng JJ, MacIntyre DL, Road JD, FitzGerald JM, Burns J, Reid WD. Falls in people with chronic obstructive pulmonary disease: an observational cohort study. Respiration Med. 2011;105(3):461-9.

    Article Google Scholar

  • Zheng DD, Christ SL, Lam BL, Feaster DJ, McCollister K, Lee DJ. Patterns of chronic illness and their association with visual impairment and health care utilization. JAMA Ophthalmol. 2020;138(4):387-94.

    Article Google Scholar

  • Stanmore EK, Oldham J, Skelton DA, O’Neill T, Pilling M, Campbell AJ, Todd C. Risk factors for falls in adults with rheumatoid arthritis: a prospective study. Arthritis Care Res. 2013;65(8):1251-8.

    Article Google Scholar

  • Torii M, Hashimoto M, Hanai A, Fujii T, Furu M, Ito H, Uozumi R, Hamaguchi M, Terao C, Yamamoto W, et al. Prevalence and factors associated with sarcopenia in patients with rheumatoid arthritis. Mod rheumatol. 2019;29(4):589-95.

    Article Google Scholar

  • Bruce M.L. Depression and Disability in Late Life: Directions for Future Research. Bin J Geriatric Psychiatry. 2001;9(2):102-12.

    Article Google Scholar

  • Hager K. Risk factors for falls and cognitive decline in the elderly. German medical journal international. 2015;112(7):101-2.

    PubMed PubMed Headquarters Google Scholar



  • Source link